Biomaterials for Regenerative WHAT IS COLTRIX®?
Collagen Scaffold for Tissue Regeneration
COLTRIX® is made up of 3% Type-I Atelo-Collagen that facilitate formation of tightly packed “helically bonded Collagen fibrils”.
COLTRIX® is made up of 3% Type-I Atelo-Collagen that facilitate formation of tightly packed “helically bonded Collagen fibrils”.
TWO VARIANTS OF SCAFFOLDS AVAILABLE
- COLTRIX® Cartiregen
Collagen Scaffold that supplements Cartilage Regeneration
- COLTRIX TendoRegen
It is used to augment Tendon and Ligament Repair
COLTRIX® PROPERTIES
- Forms highly viscous gels gel at pH 7 and 37°C
- Rapid Gel Time 5-10 minutes
- Ideal for 3D scaffolds to promote cell proliferation and migration
- Enables the production of high density scaffolds (dry sponges)
- Can be diluted to provide a broad ranges of pore sizes
- Suitable Carrier for Cells and Bioactive Molecules
- Can be mixed with living cells, BMAC/PRP or proteins such as fibrinogen
Relevance of Collagen
- Approximately 30% of all proteins in the human body are collagen
- Over 90% of the collagen in the body is Type 1
- Collagen is a Natural platelet activator!!
- Collagens are Building Blocks of Connective Tissue Matrix
- Collagen gives both strength and elasticity to tissues
Why Collagen Scaffolds?
- Low immunogenicity and biodegradable
- Porous structure with good permeability
- Regulate differentiation and migration of Osteoblasts and Osteoclasts
- Promote Synthesis of Bone and Cartilage Matrix
- 3D matrix directing regeneration of the Osteo-Cartilaginous tissue
COLTRIX® - Biomaterial for the future
- Serve as Replacement for Bone Grafts
- Applicable for All Age Groups
- Supplements PRP/Stem Cells
- Provides a Holistic Regenerative Approach
Indications
Osteoarthritis
Rotator Cuff injury
Achilles tendinitis
Plantar Fasciitis
Tennis and Golfer’s Elbow
Anterior Cruciate Ligament (ACL) Injury
